
It focuses on fighting with Devil Fruit abilities (also known as "Ability" in-game) and Haki, which can be activated by the "Ability" button which drains the ability gauge to use Haki and/or Devil Fruit abilities. Normal attacks can also be branched into other moves such as a ranged attack or a light guard break depending on the character. The guard break mechanic is also carried over from J-Stars Victory Vs., albeit in two forms: first is the weak/light guard break done with the attack + jump that can break-through guards fairly fast, and second is the heavy/strong guard break done with unique + guard that trades startup for solid tracking ability to beat sidesteps with.

There are two main attacks: normal attack and unique attack both attacks can be performed in a direction (towards the opponent or away from the opponent) for varying moves (back + attack = ranged attack while back + unique is another unique attack). Unlike most fighting games in this scheme however, Burning Blood is unique in the fact that the default guard button is not allocated to a trigger button, and is instead allocated to a standard button instead (default is circle button). alike, it is a recent fighting game to introduce an "auto-combo-into special move finisher" mechanic in its basic attack chain. Just like several fighting games and J-Stars Victory Vs. (which also features characters from One Piece), albeit in a more restricted 1-on-1 scheme along with different features. Overall, the game somewhat follows the style of prior Spike Chunsoft-developed game, J-Stars Victory Vs. However, the overall gameplay is much more akin to Spike Chunsoft's other fighting games, which primarily revolves around free-sandboxed-3D movement and basic attack strings allocated to a single button, along with specific button combinations which can allow access to special moves (holding down the special trigger button and combining it with three other basic buttons). some teams may involve 1 character with a large-handful of supports, while some teams have the 3 character limit filled with only 1 or 2 supports).

However, teams can be constructed via 1, 2 or 3 members total, with varying combinations of both playable characters and supports being limited by a number (e.g. The player can switch between characters during battles and use partners for assist attacks, such as tagging in with the Unity Chain/Assist/Clash when certain special moves properly connect (which however, can be countered by the victim's opposing Unity-based mechanic and vice versa). Similar to the Grand Battle! series, One Piece: Burning Blood is a 1-on-1 fighting game, featuring 3v3 melee style fights, where each player picks a team of 3 characters and 3 support characters.

4.1 Gold Movie Pack 1 (released August 2016):.
